13.
An efficient and high yield synthesis of Siamenoside I (1), from Mogroside V (2) is reported. Siamenoside I (1) was obtained by enzymatic hydrolysis of Mogroside V (2). Bioconversion process involved enzymatic modification followed by separation and purification processes, including reversed-phase chromatography. The final product, a dried white powder, undergoes several stages of concentration, r...
Indra Prakash *, Christopher P. Mercogliano, Gil Ma and Steven F. Sukits
The Coca-Cola Company, Atlanta, GA, 30313, USA.
DOI: 10.13040/IJPSR.0975-8232.16(8).2250-58
2250-2258
14.
New Benzimidazole derivatives were designed and synthesized. To explain the activity of new derivatives, we have explored the binding affinity of the compounds against α-amylase (PDB ID: 4W93), the target enzyme for the antidiabetic activity. α-amylase is considered as primary target because it converts starch into maltose, which is followed by the production and transportation of the glucose in...
K. P. Beena * and T. Akelesh
Department of Pharmaceutical Chemistry, Sri Ramakrishna Institute of Paramedical Sciences, College of Pharmacy, Coimbatore, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.16(8).2259-66
2259-2266
15.
Green Nanotechnology techniques have emerged in response to the growing need for sustainable and eco-friendly approaches to synthesize nanoparticles. The present study provides an endurable procedure for the green-mediated synthesis of silver nanoparticles (AgNPs) from Albizia amara leaf extract and its antibacterial potential. Various techniques like UV-Vis spectroscopy, FT-IR, XRD and FE-SEM wer...
Meera Sivakumar *, Suja Gunasekaran, Geetha Ramani Durairaj, Vinoth Kumar Thirumalairaj, Ramya Karthikeyan and Nithya Devi Murugesan
Department of Biotechnology, CMS College of Science and Commerce, Coimbatore, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.16(8).2267-74
2267-2274
16.
Alzheimer’s Disease is considered as the most common form of dementia, contributing to about 70% of the cases. The FDA approved Acetyl cholinesterase inhibitors and NMDA receptor antagonists only produce a symptomatic relief and raises the need for novel potential drug candidates for AD management. The various hypotheses on Alzheimer’s Disease reveal its multifactorial nature and thus these mu...
Sherin A. Hameed *, N. Fathima, S. Gadha, M. S. Gopika, R. V. Namitha and Sahadiya
Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Govt. Medical College, Thiruvananthapuram, Kerala, India.
DOI: 10.13040/IJPSR.0975-8232.16(8).2275-93
2275-2293
17.
Vitiligois depigmentation disorder, and it causes loss of melanocytes. Denaturation of melanocytes caused by oxidative stress, genetics, auto immune response and then synthesis of inflammatory mediators. Vitiligo is classified into two types segmental and non-segmental. There is various treatment to cure vitiligo and some treatment causes side effects. So, through herbal plants we can cure the dis...
M. Ramya * and K. Shalini
Department of Pharmacognosy, Karapaga Vinayaga Institute for Pharmaceutical Sciences, Maduranthakam, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.16(8).2294-10
2294-2310